Words similar to biglycan
Example sentences for: biglycan
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These genes include those for glucose-6-phosphate dehydrogenase, XAP-5, renin-binding protein, N -acetyltransferase (homolog of Saccharomyces cerevisiae ARD1 ), signal sequence receptor-delta, isocitrate dehydrogenase 3 (NAD +) gamma, biglycan, tafazzin, deoxyribonuclease I-like 1, and emerin [ 51].
The presence of TGF-β increases the expression of such extracellular matrix proteins as fibronectin, the fibronectin receptor, vitronectin, tenascin, elastin, thrombospondin, collagen, and biglycan [ 25 26 27 28 29 30 31 32 ] and also inhibits expression of proteases that degrade the extracellular matrix while stimulating the expression of protease inhibitors [ 33 34 35 36 ] .
Lumican expression has previously been correlated with higher tumor grade, lower estrogen levels in the tumor and younger age of patients in human breast cancer [ 21 ] . In addition, lumican is structurally related to both biglycan which is among the top IL-8-tumor related genes and the human embryonal carcinoma marker antigen TRA-1-60 [ 22 ] . These relationships support the hypothesis that lumican may be a tumor related protein involved with IL-8's tumorigenic function.