Example sentences for: bicuculline

How can you use “bicuculline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Work in this laboratory has shown lags in neuromuscular development associated with excessive zinc exposure during neural tube formation and, possibly, accompanying narrowing of the vertebral arches [ 26 ] . Another curious finding of this study is that widening of the vertebral arch occurs with either the GABAa agonist muscimol or the antagonist bicuculline.

  • As a matter of fact it was suggested that the gap junction coupling state between neurons in SCN is not static but dynamically regulated by the GABA A receptor system [ 14 ] . Also in vitro guinea-pig brain preparation prolonged seizure-like activity elicited using a brief application of bicuculline was abolished by the GJ channel blockers octanol and glycyrrhetinic acid as well as by intracellular acidification [ 16 ] .

  • Effects of bicuculline

  • Chemicals used in the experiment consisted of bicuculline methiodide (BMI), kynurenic acid (Sigma, St. Louis, MO) and QX-314 (Tocris).

  • Depolarization propagation was also inhibited by muscimol, a GABA A receptor agonist, in a dose dependent manner, and inhibition was reversed by bicuculline, a GABA A receptor antagonist.


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