Words similar to bicuculline

Example sentences for: bicuculline

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As a matter of fact it was suggested that the gap junction coupling state between neurons in SCN is not static but dynamically regulated by the GABA A receptor system [ 14 ] . Also in vitro guinea-pig brain preparation prolonged seizure-like activity elicited using a brief application of bicuculline was abolished by the GJ channel blockers octanol and glycyrrhetinic acid as well as by intracellular acidification [ 16 ] .
Depolarization propagation was also inhibited by muscimol, a GABA A receptor agonist, in a dose dependent manner, and inhibition was reversed by bicuculline, a GABA A receptor antagonist.
Work in this laboratory has shown lags in neuromuscular development associated with excessive zinc exposure during neural tube formation and, possibly, accompanying narrowing of the vertebral arches [ 26 ] . Another curious finding of this study is that widening of the vertebral arch occurs with either the GABAa agonist muscimol or the antagonist bicuculline.
Effects of bicuculline
The specific GABA A receptor antagonist, bicuculline, blocks the γ oscillations [ 14 16 ] , an action that can be modeled by simulated neuronal networks [ 17 ] . The γ band oscillations appear to play an important role in generation of ictal epileptiform activity in hippocampal slices [ 18 ] . This study explores the role of γ oscillations in epileptiform activity in the hyperthermic rat hippocampal slice.