Example sentences for: bicuculline

How can you use “bicuculline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a matter of fact it was suggested that the gap junction coupling state between neurons in SCN is not static but dynamically regulated by the GABA A receptor system [ 14 ] . Also in vitro guinea-pig brain preparation prolonged seizure-like activity elicited using a brief application of bicuculline was abolished by the GJ channel blockers octanol and glycyrrhetinic acid as well as by intracellular acidification [ 16 ] .

  • Effects of bicuculline

  • The GABAa antagonist bicuculline also widened vertebral arch distance at the 0.5 and 1 mg/kg doses (p < .05), but not at the 2 mg/kg dose.

  • The specific GABA A receptor antagonist, bicuculline, blocks the γ oscillations [ 14 16 ] , an action that can be modeled by simulated neuronal networks [ 17 ] . The γ band oscillations appear to play an important role in generation of ictal epileptiform activity in hippocampal slices [ 18 ] . This study explores the role of γ oscillations in epileptiform activity in the hyperthermic rat hippocampal slice.

  • Work in this laboratory has shown lags in neuromuscular development associated with excessive zinc exposure during neural tube formation and, possibly, accompanying narrowing of the vertebral arches [ 26 ] . Another curious finding of this study is that widening of the vertebral arch occurs with either the GABAa agonist muscimol or the antagonist bicuculline.


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