Words similar to bicuculline

Example sentences for: bicuculline

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The specific GABA A receptor antagonist, bicuculline, blocks the γ oscillations [ 14 16 ] , an action that can be modeled by simulated neuronal networks [ 17 ] . The γ band oscillations appear to play an important role in generation of ictal epileptiform activity in hippocampal slices [ 18 ] . This study explores the role of γ oscillations in epileptiform activity in the hyperthermic rat hippocampal slice.
Chemicals used in the experiment consisted of bicuculline methiodide (BMI), kynurenic acid (Sigma, St. Louis, MO) and QX-314 (Tocris).
The GABAa antagonist bicuculline also widened vertebral arch distance at the 0.5 and 1 mg/kg doses (p < .05), but not at the 2 mg/kg dose.
Bicuculline is a well-documented specific and potent GABAa antagonist [ 33 ] .
We utilized the specific GABA A receptor antagonist, bicuculline methiodide (BMI), to ascertain whether γ oscillations were dependent upon GABAergic mechanisms.