Words similar to bicistronic

Example sentences for: bicistronic

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For example, Snrpn (small nuclear ribonucleoprotein N; MGI: 98347) and Snurf ( SNRPN upstream reading frame; MGI: 1891236) are expressed as bicistronic Snurf-Snrpn transcript [ 27] and both of them were associated with one single TC (TC619385) and one single DT (DT.
JC constructed and characterized the bicistronic reporter constructs and aided with manuscript preparation.
To test this, a 472 nucleotide fragment, representing the full-length human p27 Kip15'-UTR derived from transcription initiation at the major start site, was inserted into the bicistronic expression vector pGL2CAT/Luc [ 30 ] . In this vector, the first cistron, encoding chloramphenicol acetyltransferase (CAT), is proximal to the mRNA's cap structure and therefore expected to be translated by the conventional cap-dependent translation mode.
The effect of constitutively active 4EBP-1 on the activity of the p27 Kip15'-UTR was determined by cotransfecting the bicistronic construct together with an expression vector encoding 4EBP-1-5A into MCF7 cells.
This property is shared by the highly homologous mouse p27 Kip15'-UTR [ 28 ] . Coexpression of 4EBP-1-5A with the bicistronic construct containing the p27 Kip15'-UTR leads to an approximately two-fold increase in cap-independent expression.