Example sentences for: biallelic

How can you use “biallelic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If the P2 primer is common to both OCPs, only P1 priming efficiencies need to be similar, greatly simplifying the process of obtaining balanced reaction kinetics in a biallelic assay.

  • There are a number of advantages to having both probes present in the same reaction, as opposed to having each probe in a separate reaction [ 3 ] . For instance, if amplification fails in a biallelic (ie.

  • An observation of four different haplotypes from a pair of biallelic loci was considered evidence for recombination or recurrent mutation.

  • Similarly, OCP ligation/ERCA can be used to accurately genotype PCR products in a biallelic format, where the probes for both alleles are present in a single reaction [ 3 ] . The OCP ligation/ERCA method is based on ligation dependent circularization of allele specific DNA probes followed by exponential rolling circle amplification of the circularized probes [ 4 5 ] . ERCA probes have also been variously described as 'padlock probes' [ 6 7 ] or 'circularizable probes' [ 4 ] . Although OCP ligation/ERCA can be used to genotype PCR products, it also provides a means for directly genotyping genomic DNA without requiring an initial amplification of the genomic DNA locus.

  • P1 primers were routinely titrated to determine optimum concentration [ 4 ] . This approach greatly reduces the difficulty of balancing the kinetics of biallelic ERCA amplifications.


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