Words similar to benzyl
Example sentences for: benzyl
How can you use “benzyl” in a sentence? Here are some example sentences to help you improve your vocabulary:
In order to determine the nature of the amino acids interacting with the distal amino and N-benzyl groups of lerisetron, we constructed 5-HT 3AS Rs containing mutations at W89, R91, Y140, Y142 and Y152.
Importance of the N-benzyl and distal piperazine nitrogen to binding of lerisetron
Since the K i for analog 1 is increased by the Y152A mutation, it is unlikely that the N-benzyl group interacts with Y152.
The interaction between lerisetron and W89 is unlikely to be via the N-benzyl functional group since the K i for analog 1 was also altered by this mutation.
The increases in the K i values were 190 fold for lerisetron, 98 fold for analog 1 and only 40 fold for analog 2. Thus, analog 1 retains much of its ability to interact with Y152 despite the absence of the N-benzyl group, while analog 2 interacts more weakly with this amino acid.