Example sentences for: bax

How can you use “bax” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • There was an increase in caspase-3 and Bax mRNA levels at 4 weeks.

  • Additionally, since the identification and cloning of the p27 gene in 1994 [ 16 ] , the p27 protein has been shown to be involved in various other aspects of cell physiology and pathology [ 17 ] . Our previous study has shown, that differentiation of cells in tissue culture is associated with an increase in p27 expression [ 18 ] . Although a regular p27 expression protects normal cells from apoptosis, overexpression of p27 induces apoptosis of cells, through elevation of proapoptotic proteins, such as Bax [ 19 20 ] . These observations indicate that changes in p27 expression can determine the fate of muscle cells.

  • We were also unable to detect Bax or Bcl-X L in rat adherent vascular lung neutrophils, which is in contrast to results with human peripheral blood neutrophils [ 30 31 ] . These differences may be due to unique attributes of human and rat cells, their distinct location in the vasculature, and/or to their exposure to inflammatory stimuli in vivo .

  • Cells transformed with mutated ras exhibit a defect in the signal transduction pathway regulating p53 function and alteration in the expression of apoptotic (bax) or anti-apoptotic proteins (bcl-2) [ 20].

  • tBid and other pro-death proteins such as Bax or Bak could destabilize the membrane leading to the observed changes.


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