Example sentences for: bax

How can you use “bax” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In support of this hypothesis, it has been shown that p53 and BRCA1 can form stable complexes, and can coactivate p21 and bax genes, which may lead to the activation of the apoptosis pathway [ 15].

  • Additionally, since the identification and cloning of the p27 gene in 1994 [ 16 ] , the p27 protein has been shown to be involved in various other aspects of cell physiology and pathology [ 17 ] . Our previous study has shown, that differentiation of cells in tissue culture is associated with an increase in p27 expression [ 18 ] . Although a regular p27 expression protects normal cells from apoptosis, overexpression of p27 induces apoptosis of cells, through elevation of proapoptotic proteins, such as Bax [ 19 20 ] . These observations indicate that changes in p27 expression can determine the fate of muscle cells.

  • Apoptosis related molecules, such as Bcl-xS, Bax, and casepase-3, are known to be proapoptotic factors and involved in variety of vessel remodeling processes [ 37 38 39 ] . The initial arrest in Bcl-xS gene expression may momentarily depress apoptosis.

  • Expression of apoptosis-related molecules, such as Bcl-xS, Bax, and caspase-3, seems to be little regulated in the early stage of this vessel remodeling process.

  • tBid and other pro-death proteins such as Bax or Bak could destabilize the membrane leading to the observed changes.


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