Words similar to bax
Example sentences for: bax
How can you use “bax” in a sentence? Here are some example sentences to help you improve your vocabulary:
There was an increase in caspase-3 and Bax mRNA levels at 4W.
Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.
Bak migrates to the mitochondrial outer membrane where it generates transmembrane pores; Bax induces the opening of the mitochondrial permeability transition pores.
Additionally, since the identification and cloning of the p27 gene in 1994 [ 16 ] , the p27 protein has been shown to be involved in various other aspects of cell physiology and pathology [ 17 ] . Our previous study has shown, that differentiation of cells in tissue culture is associated with an increase in p27 expression [ 18 ] . Although a regular p27 expression protects normal cells from apoptosis, overexpression of p27 induces apoptosis of cells, through elevation of proapoptotic proteins, such as Bax [ 19 20 ] . These observations indicate that changes in p27 expression can determine the fate of muscle cells.
1and 2) and was shown to destabilize lipid membranes in vitro (along with Bax) by increasing the permeabilization of artificial liposomes [ 25 26 ] . Therefore it is possible that tBid can bind to the cardiolipin rich contact site membranes and destabilize them by inducing Bax or Bak to oligomerize.
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