Example sentences for: backcrossed

How can you use “backcrossed” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These IL-10 -/-mice were backcrossed to DBA/1 for six generations and further backcrossed for an additional two generations to DBA/1 (Jackson Laboratories, Bar Harbor, MA, USA) in our laboratory.

  • Although the chimeric mice are usually backcrossed to B6 to dilute the contribution of the 129 genome, the knockout strains are always a mixture of the two genomes (Figure 1).

  • The mutants displaying the strongest GFP-Nup mislocalization phenotypes were backcrossed.

  • The Y chromosome has been implicated in strain specific blood pressure differences in rats [ 23 24 ] . To test if the Y chromosome of strain 129/Ola alters IOP in relation to that of strain B6, we compared the IOPs of pure B6 males and consomic B6 males that had the 129P2/Ola Y chromosome (backcrossed for 11 generations).

  • Tag-TCR1 (referred to hereafter as TCR) transgenic mice expressing a T cell receptor transgene with specificity to Tag were generated in the B6D2F1 background and backcrossed to C3HeBFe for 20 generations [ 28 ] . About 10% of the splenic CD4 +T cells in this transgenic line express the TCR transgene [ 28 ] . All Rip1-Tag2 in all treatment groups received the same diet throughout the experiment.


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