Example sentences for: backbone

How can you use “backbone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 27 ] Generating peptide backbones sufficiently close to the native backbone to allow packing algorithms is still a challenge.

  • To solve the problem of cell penetration, most researchers have either complexed the RNA with a lipid or modified the RNA's phosphate backbone to minimize its charge.

  • The alkyl backbone of the transported glycerol is adjacent to the hydrophobic surface and the hydroxyl groups form hydrogen bonds with the hydrophilic surfaces [ 23, 24].

  • In the former case, the DNA backbone sites located closest to one another are across the minor groove and separated in sequence by 3 bp [ 28 29 30 ] . The second proposal is supported by a recent 2.2 angstrom NarL-DNA structure for NarL-C-terminal domain complexed to a synthetic 7-2-7 NarL consensus binding site where the protein causes a conformational change of B-DNA to A-DNA (Ann Maris, personal communication).

  • This might be due to the polysaccharide backbone of cellulose [ 60 ] with a propensity to form strong intermolecular hydrogen bonds and to be involved in hydrophobic interactions more than soluble dextrans [ 61 ] and galactose + 3,6-anhydrogalactose copolymers (= the saccharide moiety of carrageenan) [ 62 63 ] . Among the two polymers containing aryl sulfonates, poly(napthalene sulfonate) was more effective than poly(styrene-4-sulfonate) with respect to induction of gp41 six-helix bundles in HIV-1 BaL.


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