Words similar to b-dna
Example sentences for: b-dna
How can you use “b-dna” in a sentence? Here are some example sentences to help you improve your vocabulary:
In giving her final seminar, she switched from her earlier insistence that B-DNA was nonhelical, but did not show the photo that gave the strongest evidence for helicity.
In January, Raymond Gosling gave to Wilkins the very well-oriented diffraction photo of B-DNA that he and Franklin had taken in July 1952.
Mysteriously, she put aside a striking photo of the diffraction pattern of B-DNA (one of the two major structural forms of DNA) that emerged in early 1953 as a perfect signature of the helical form.
They found a unique way to fit the bases in the structure by pairing, and by March 7 they had the double-helix model constructed: it obeyed the Chargaff ratios, it fit the X-ray data for B-DNA, and it provided a rational way to encode and transmit genetic information to subsequent generations.
CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .
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