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How can you use “aβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To date, however, this mechanism is not supported by data from human clinical trials, where statin administration has shown no consistent effect on levels of circulating or cerebrospinal fluid [73].

  • These neurons receive monosynaptic input from Aδ and fibers.

  • In cell culture, lovastatin and simvastatin decrease the release of by rat hippocampal neurons [12,14] while activating α-secretase-type ectodomain shedding [15,16].

  • Cao and Sudhof [56] have recently discovered that the APP C-terminal fragment generated by α- or β-secretase is itself cleaved to release and an APP intracellular domain (AICD) that diffuses into the nucleus, possibly acting there as a transcription factor.

  • These deposits are composed of amyloid-beta () peptide, a protein fragment that is cleaved off from the amyloid precursor protein APP.


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