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How can you use “aβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • α-Secretase-type ectodomain shedding divides the domain of APP, thereby generating α-secretase-cleaved soluble APP ectodomain (sAPP α ) [4].

  • Cao and Sudhof [56] have recently discovered that the APP C-terminal fragment generated by α- or β-secretase is itself cleaved to release and an APP intracellular domain (AICD) that diffuses into the nucleus, possibly acting there as a transcription factor.

  • sAPP α and sAPP β differ by the inclusion in sAPP α of the first 16 residues of .

  • These deposits are composed of amyloid-beta () peptide, a protein fragment that is cleaved off from the amyloid precursor protein APP.

  • Furthermore, in humans, it is now clear that there are four isoforms of PP1 [PP1α, PP1δ, PP1γ 1 and PP1γ 2 [ 11, 12, 13], two isoforms of PP2A (PP2A α and PP2Aβ [ 14, 15]) and four structurally related phosphatases, PP4 [ 16], PP5 [ 17, 18], PP6 [ 19] and PP7 [ 20].


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