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How can you use “aβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Reduction in levels of free in the circulation has been demonstrated to lead to diminution in brain plaque burden following active or passive immunization [72].

  • In cell culture, lovastatin and simvastatin decrease the release of by rat hippocampal neurons [12,14] while activating α-secretase-type ectodomain shedding [15,16].

  • These neurons receive monosynaptic input from Aδ and fibers.

  • α-Secretase activation may explain how statins lower the risk for Alzheimer disease [69], since atorvastatin diminishes burden in plaque-forming transgenic mice [13].

  • It is conceivable that, if statins lower circulating , this effect could secondarily cause diffusion of central nervous system interstitial down its concentration gradient and into the cerebrospinal fluid and circulation, from which it is cleared.


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