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How can you use “aβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These neurons receive monosynaptic input from Aδ and fibers.

  • Amyloid deposits are composed of the amyloid-β peptide (), a 4-kDa peptide released during “amyloidogenic” proteolytic processing of the Alzheimer precursor protein (APP) [2].

  • To date, however, this mechanism is not supported by data from human clinical trials, where statin administration has shown no consistent effect on levels of circulating or cerebrospinal fluid [73].

  • These investigators discovered that activation of ROCK1 may account for how nonsteroidal anti-inflammatory drugs specify the scissile bond within the APP transmembrane domain that is cleaved by presenilin/γ-secretase to generate the C-terminus of .

  • Cao and Sudhof [56] have recently discovered that the APP C-terminal fragment generated by α- or β-secretase is itself cleaved to release and an APP intracellular domain (AICD) that diffuses into the nucleus, possibly acting there as a transcription factor.


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