Words similar to axin

Example sentences for: axin

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These results are consistent with claims that LRPs can signal through an interaction of the carboxyterminus with Axin [ 13 ] .
Similar results were reported for this FLAG epitope-tagged mutant in other cell lines [ 26 ] . Second, the tail kinking and "waltzing" phenotypes in our transgenic animals expressing stabilized human β-catenin are highly similar to those seen in Fused mice [ 29 ] . Fused encodes the murine Axin homologue, and mutation of this gene results in activation of Wnt signaling [ 30 ] . The tail kinking in our animals presumably results from low level expression of the mutant transgene in utero during vertebral patterning.
The tail kinking in these mice is highly similar to the phenotype seen in Axin mutants with activated Wnt signaling, indicating the β-catenin protein expressed in our transgenic mice is functional.
Dsh in turn inhibits glycogen synthase kinase (GSK)-3β in the β-catenin destruction complex, which mainly consists of Axin, GSK-3β, adenomatous polyposis coli (APC) and β-catenin.
In agreement with this possibility, an intracellular domain of LRP5 was reported to interact directly with Axin [ 13 ] , and Wnt signaling appears to stimulate the recruitment of Axin to LRP5 at the membrane, where Axin is degraded.