Example sentences for: axin

How can you use “axin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.

  • These results are consistent with claims that LRPs can signal through an interaction of the carboxyterminus with Axin [ 13 ] .

  • In agreement with this possibility, an intracellular domain of LRP5 was reported to interact directly with Axin [ 13 ] , and Wnt signaling appears to stimulate the recruitment of Axin to LRP5 at the membrane, where Axin is degraded.

  • The tail kinking in these mice is highly similar to the phenotype seen in Axin mutants with activated Wnt signaling, indicating the β-catenin protein expressed in our transgenic mice is functional.

  • Similar results were reported for this FLAG epitope-tagged mutant in other cell lines [ 26 ] . Second, the tail kinking and "waltzing" phenotypes in our transgenic animals expressing stabilized human β-catenin are highly similar to those seen in Fused mice [ 29 ] . Fused encodes the murine Axin homologue, and mutation of this gene results in activation of Wnt signaling [ 30 ] . The tail kinking in our animals presumably results from low level expression of the mutant transgene in utero during vertebral patterning.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast