Example sentences for: axin

How can you use “axin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The tail kinking in these mice is highly similar to the phenotype seen in Axin mutants with activated Wnt signaling, indicating the β-catenin protein expressed in our transgenic mice is functional.

  • If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.

  • These results are consistent with claims that LRPs can signal through an interaction of the carboxyterminus with Axin [ 13 ] .

  • Dsh in turn inhibits glycogen synthase kinase (GSK)-3β in the β-catenin destruction complex, which mainly consists of Axin, GSK-3β, adenomatous polyposis coli (APC) and β-catenin.

  • While the functions of Fz and Dsh remain to be clarified, it is possible that upon Wnt signaling, Fzs recruit Dsh to the membrane and Dsh brings Axin to the carboxyterminus of LRPs.


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