Words similar to avp
Example sentences for: avp
How can you use “avp” in a sentence? Here are some example sentences to help you improve your vocabulary:
The behavioral effects of AVP are not limited to flank marking in hamsters.
The concentrations of AVP required to induce flank marking are low (ranging from 0.1 to 100 μM) [ 4 5 ] and the volumes microinjected in the anterior hypothalamus are small (ranging from 20 to 100 nl).
Future studies could focus on effects of long-term elevation of AVP in hamsters; dose-response manipulations of psychotropics or clinical use of AVP receptor antagonists on humans to further investigate the role of AVP in OCD.
As noted, the microinjection of 10 μM AVP causes maximal flank marking, hence it is likely the inhibition of behavior with drug treatment might have been more pronounced if the animals were challenged with lower doses of AVP.
Indeed, alterations in AVP regulation and secretion are thought to be one possible biochemical abnormality in patients with Obsessive Compulsive Disorder (OCD) [ 15 16 17 18 ] . This disorder is characterized by sudden, recurrent thoughts or images that intrude into consciousness (obsessions) driving stereotyped acts that the person feels compelled to perform (compulsions) [ 19 ] . Interestingly, patients with OCD show elevated basal levels of AVP in the cerebrospinal fluid and exaggerated plasma levels of AVP in response to hypertonic challenge [ 16 ] . Many patients with anorexia nervosa and bulimia nervosa, both compulsive eating disorders, have abnormal levels of AVP in the cerebrospinal fluid and plasma [ 15 17 ] . Pediatric patients with severe OCD have low levels of AVP in cerebrospinal fluid, while a subgroup of pediatric patients with compulsive checking rituals has elevated AVP levels [ 18 ] . Hence, there are many clinical examples of compulsive behavior associated with a perturbation in the AVP system.
Loading...