Example sentences for: autosomal

How can you use “autosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The first autosomal dominant form of cardiomyopathy was mapped in 1994 to the centromeric region of chromosome 1 [ 9 ] . Linkage was achieved using genetic and clinical material from a large, well-characterized kindred [ 1 ] . One of the striking characteristics from this family was the degree of cardiac conduction system disease that primarily targeted the atrioventricular node [ 1 10 ] . Many members of the kindred exhibited sick sinus syndrome, atrial fibrillation and sudden death.

  • The normal staining pattern of sarcospan in the autosomal dominant CFEOM1 patient muscle indicates that the primary genetic mutation is likely to be found in another, unrelated gene.

  • The family includes the Y-linked DAZ genes that are present only in great apes and old world monkeys [ 3 ] , and the autosomal DAZL1 (DAZ-like 1) and BOULE genes [ 4 5 ] in all mammals.

  • In the reported family whose autosomal dominant CFEOM3 phenotype maps to the FEOM3 locus, 9 of the 17 affected members had classic CFEOM.

  • Indeed, a rapid search of the Online Mendelian Inheritance in Man database (OMIM [ 18]) for genes associated with the terms 'severe' and 'disorder' confirmed that mutations of GALC, LAMB3, GJB2, JAG1, TGFBI, LPL and LDLR were the origin of serious disorders: Krabbe disease, Herlitz junctional epidermolysis bullosa, autosomal dominant deafness - Vohwinkel syndrome, Alagille syndrome, corneal dystrophy, type I hyperlipoproteinemia and hypercholesterolemia, respectively.


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