Example sentences for: autosomal

How can you use “autosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ataxia telangiectasia mutated gene (ATM) is a newly identified member of PI3 kinase family that is mutated in human autosomal recessive disease, ataxia telangiectasia (AT) [ 12 13 ] . ATM gene is large, spanning about 150 kbs of genomic DNA, and is located on chromosome 11q22-23.

  • CFEOM1 is an autosomal dominant disorder that has been linked to the pericentromere of chromosome 12, flanked by marker D12S1584 on the p arm and D12S1668 on the q arm [ 1, 2].

  • The human disorder of sitosterolemia, also known as phytosterolemia (MIM 210250), is an autosomal recessive disorder characterized by the marked elevation of plasma phytosterols e.g. β-sitosterol, campesterol and stigmasterol [ 1 2 ] . Hypercholesterolemia primarily during childhood, accelerated atherosclerosis in some adult patients leading to premature death, as well a hemolytic anaemia, arthralgias and tendon and tuberous xanthoma formations are other clinical features.

  • Because the scaffold contains two well studied autosomal heterochromatic genes, light and concertina , analysis of its sequence provides an opportunity to assess the accuracy of both the WGS3 sequence assembly and the annotation process over an extended heterochromatic region.

  • Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.


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