Words similar to autosomal
Example sentences for: autosomal
How can you use “autosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:
The autosomal coverage was estimated to be 12x [ 1]; thus, sequence coverage is expected to be 9× for the X chromosome, and 3x for the Y, assuming an equal number of male and female embryos in the collection used to make the DNA for the WGS.
Model-dependent linkage analysis has been used in large pedigrees with diseases such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) [ 6 7 8 9 ] . However, traditional linkage analysis is unlikely to be the most expedient method of finding novel stroke-susceptibility genes when carrier status cannot be defined on the basis of distinctive clinical, radiographic, or laboratory features.
Ataxia telangiectasia mutated gene (ATM) is a newly identified member of PI3 kinase family that is mutated in human autosomal recessive disease, ataxia telangiectasia (AT) [ 12 13 ] . ATM gene is large, spanning about 150 kbs of genomic DNA, and is located on chromosome 11q22-23.
Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.
Comparative transcription profiling of matched pairs of fibroblast clones should eliminate any noise contributed by polymorphisms or mutations of autosomal genes.
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