Words similar to autophosphorylation
Example sentences for: autophosphorylation
How can you use “autophosphorylation” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, the Src inhibitor, PP1 or the expression of a dominant-negative Src mutant, will reduce GPCR-mediated transphosphorylation of the EGFR and GPCR-mediated ERK activation to varying degrees (partial to total), suggesting that at least two different tyrosine kinases can be involved [ 18 ] . Src was found to co-immunoprecipitate with the phosphorylated EGFR in COS-7 cells exposed to either LPA or EGF [ 14 ] . These authors reported that the autophosphorylation of Y350 in the EGFR does not occur after LPA exposure, suggesting that c-Src is the principal tyrosine kinase in this instance and not the EGFR's intrinsic tyrosine kinase.
To test the function of the virally encoded receptors, we measured IGF-I stimulated autophosphorylation of the IGF-IR and phosphorylation of IRS-1.
Fig 1Bshows that WT Btk:ER was kinase active in vitro as determined by autophosphorylation and phosphorylation of an exogenous substrate (GST-Igα) in an immune-complex kinase assay.
max of the enzyme 50-fold [ 25 ] . To test for similar autophosphorylation regulation of MHCK-C, we tested the activity of FLAG-MHCK-C with and without an initial autophosphorylation step, towards the peptide substrate MH-1 (a 16-residue peptide corresponding to one of the mapped MHC phosphorylation target sites for MHCK A in the myosin tail).
It has been proposed that Src kinases activate Btk through phosphorylation of a tyrosine, Y551 in the activation loop of Btk, leading to increased kinase activity and autophosphorylation of a tyrosine in the SH3 domain.
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