Example sentences for: autocrine

How can you use “autocrine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recent work by Hasty and coworkers [ 3] has demonstrated that local expression of IL-1β by articular chondrocytes activates autocrine gene expression, which contributes to the pathogenesis of osteoarthritis (OA).

  • Transformation appears to involve autocrine stimulation as IGF-I production and secretion is increased in normal cells following transformation by SV40 T antigen, but the null cells cannot respond to the IGF-I so do not transform.

  • An autocrine effect of conceptus estrogen synthesis has been suggested as filamentous conceptuses have greater gene expression for estrogen receptor β compared to its spherical and tubular counterparts [ 9 ] .

  • The role of hormones in this process is clear; however, new results indicate that autocrine/paracrine or growth factor mechanisms also have important roles.

  • Very little is known about the role of the TE in folliculogenesis: however this new finding raises the possibility that BMP-3b and -4 could have autocrine actions on TE histogenesis and/or paracrine actions on theca/follicle morphogenesis.


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