Words similar to atypical
Example sentences for: atypical
How can you use “atypical” in a sentence? Here are some example sentences to help you improve your vocabulary:
In particular, we have found that Btk-deficient DT40 cells reconstituted with Txk, an atypical Tec family PTK, fail to undergo BCR-induced JNK activation (Tomlinson and Johnston, unpublished data) and apoptosis [ 13], but ERK activation is relatively normal [ 13].
Olanzapine is a newer atypical antipsychotic agent with a pharmacological profile very similar to that of clozapine [ 11 ] . In human brain tissue, olanzapine displays very high affinity for the H1 histamine receptor, high affinity for 5-HT2A and 5-HT2C receptors [ 12 ] . In addition it also shows affinity for D2, muscarinic, and alpha1 receptors, with lower affinity for alpha2, 5-HT1D and 5-HT1A receptors (Table 1 [ 12 ] ).
When reversal of depression is an immediate short-term goal, a rapid-acting psychostimulant (such as methylphenidate) is the best choice [ 38 ] . If a response in 2 to 4 weeks is acceptable, an atypical antidepressant or selective serotonin reuptake inhibitor (SSRI) may be an appropriate choice [ 39 ] . Tricyclic antidepressants have limited usefulness due to their long time to achieve therapeutic levels and risk of anticholinergic adverse effects [ 40 ] . If the diagnosis is unclear, or the expected therapeutic response delayed, consult with a colleague with expertise.
The annotation rules promote consistency in the annotation effort, and deal with all aspects of annotation: from assessment of whether a marginal gene prediction should be the basis for a new gene model to the annotation of atypical splice sites; from the determination of alternative transcriptional starts and stops, and the designation of translation starts, to the use of comments to flag atypical or questionable annotations.
Cases with insufficient, atypical, or conflicting data that the rules did not address were left to the discretion of the annotator; in such instances, comments to document the subjective nature of the gene model were added.
Loading...