Words similar to atpase
Example sentences for: atpase
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Mycobacteria enter macrophages primarily by conventional receptor-mediated phagocytic pathways [ 3 ] . Following phagocytosis, phagosomes containing viable tubercle bacilli fail to acidify, apparently because of failure to insert a proton-ATPase pump into the phagosomal membrane [ 4 5 6 ] . This leads to altered vacuolar maturation such that phagosome-lysosome fusion is blocked and the mycobacteria-containing vacuoles end up with an internal pH of about 6 and markers of phagosomes and early and late endosomes [ 7 8 9 10 11 ] . The mycobacterial genes responsible for these processes are largely unknown.
It is conceivable that over-expression of the ATPase 6 gene can be a diagnostic marker if it is unique to P. carinii infection.
Recent evidence suggested that adrenaline-induced hypokalemia resulted from stimulation of a β-adrenoceptor linked to membrane Na +/K +-ATPase, causing potassium influx [ 5 28 ] . On the other hand, there was no correlation between serum cate-cholamine level and QTc interval in the present series.
Analysis of the discordant oligonucleotide sequences (that is, inositol-1,4,5-trisphosphate receptor, H +-ATPase, branched aminotransferase and epoxide hydrolase) did not reveal any obvious secondary structure that might interfere with hybridization.
The effects of mefloquine on ER calcium homeostasis have been examined previously [ 5 6 ] . In experiments with isolated rabbit skeletal muscle microsomes, mefloquine was found to inhibit the uptake of calcium, with an IC 50 of approximately 43 μM [ 6 ] . This effect was exacerbated by treatment with thapsigargin, a specific inhibitor of the ER calcium pump [ 6 ] . Further, the rate of ATP hydrolysis by the ER Ca 2+-ATPase was reduced in the presence of mefloquine (Ki of = 53 μM).
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