Words similar to atp-grasp
Example sentences for: atp-grasp
How can you use “atp-grasp” in a sentence? Here are some example sentences to help you improve your vocabulary:
The ATP-grasp superfamily [ 41] includes at least 15 families of enzymes that catalyze formation of a bond between a carboxylate group of one substrate and an amino, imino or thiol group of a second substrate.
If this part of the protein does indeed function as a glutathione synthetase, then this would be another example of independent recruitment of an ATP-grasp superfamily member to provide this function.
Clostridium perfringens, Listeria monocytogenes, Listeria innocuans and Pasteurella multocidans have an open reading frame (ORF) that could encode a GshA homolog fused to an ATP-grasp superfamily member, raising the possibility that this protein might combine the two activities required for synthesis of GSH.
The question of whether eukaryotic GshBs are members of the ATP-grasp superfamily is difficult to answer with certainty because the eukaryotic GshBs are so dramatically different from the other superfamily members.
After multiple iterations, a PSI-BLAST search using the E. coli GshB (gi121663) as an initial query sequence found 509 sequences of enzymes in the ATP-grasp superfamily, to which the bacterial enzyme is known to belong, but no eukaryotic GshB sequences.