Words similar to atp-grasp
Example sentences for: atp-grasp
How can you use “atp-grasp” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two motifs (1 and 5) that contribute to the ATP-binding pocket were found in both eukaryotic and bacterial GshBs, as well as other members of the ATP-grasp super-family.
In fact, members of the ATP-grasp superfamily that catalyze comparable reactions (that is, GshBs (see further below), ribosomal S6 modification enzymes, D-Ala-D-Ala ligases) are sufficiently well conserved to be easily detected by PSI-BLAST, even though they utilize different substrates [ 36].
If this part of the protein does indeed function as a glutathione synthetase, then this would be another example of independent recruitment of an ATP-grasp superfamily member to provide this function.
We feel that the evidence for a true evolutionary relationship between the eukaryotic GshBs and the ATP-grasp superfamily is rather weak given the evidence available at this time.
It is particularly interesting that, in both the bacterial and eukaryotic lineages, the ATP-grasp structural fold provided the starting point for the evolution of GshB.
Loading...