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Example sentences for: atcop

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On the other hand, the site responsible for speckle formation is mapped within the cytoplasmic localization signal in AtCOP1 [ [ 19 ] ; Fig 8].
GFP-N280 (amino acid 71-350), which contains the RING finger and the coiled-coil domain, but not the sequence corresponding to the NLS in AtCOP1, is also solely localized in the nucleus (Fig 5Aand 5B).
It is worth noting that deletion constructs of AtCOP1 covering the corresponding region were found localized predominantly in the cytoplasm, distinct from the mouse GFP-N280 fusion proteins [ 17 ] .
A partial cDNA clone homologous to AtCOP1 has been previously identified in mammals, containing all three conserved protein-protein interaction domains [ 20 ] . Remarkably, when expressed in plant cells, the mammalian COP1-reporter fusion protein exhibited a light-regulated nuclear localization pattern similar to AtCOP1 [ 20 ] . Although mammalian COP1 failed to rescue the Arabidopsis cop1 mutants, over-expression of the amino-terminal half of mammalian COP1 in Arabidopsis caused a dominant-negative phenotype, resembling the effect of over-expressing the corresponding fragment of AtCOP1 [ 20 21 ] .
Similarly, AtCOP1 does not contain this region and is not located to NE [ 14 ] .