Words similar to at-hook

Example sentences for: at-hook

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Well studied examples of these are the bromodomain that interacts with acetylated peptides [ 14, 15, 16], chromodomains that mediate specific interactions with proteins [ 17, 18] and RNA [ 19, 20], the PHD finger mediating protein-protein interactions [ 21], the Myb and SANT domains [ 22] that interact with both DNA and proteins [ 23], and the SAP and AT-hook domains that interact with DNA [ 24, 25].
These may be binding sites for the S. pombe Origin Recognition Complex (ORC), whose fourth largest subunit (Orp4) contains a multiple AT-hook domain, which permits it to bind with high affinity to DNA containing runs of adenines or thymines in one strand [ 14, 15].
The AT-hook is a simple, small protein module that consists of a flap-like structure with a positively charged surface that is inserted into the minor groove of DNA [ 74 ] . The two AT-hook-like modules (residues 583-603 of 1IW7 chain D) in the DDRP β' subunit are inserted within the α-helix that is located immediately upstream of the DPBB domain (Fig.
Additionally, two AT-hook like modules, which probably had an accessory DNA-binding function, were also inserted into a conserved α-helix directly N-terminal of the DPBB domain in the β' subunit.
A potential additional nucleic-acid-binding moiety that is conserved in all β'-subunits is the AT-hook like module (Fig.