Words similar to asymptomatic
Example sentences for: asymptomatic
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Despite this common genetic background, phenotypic expression of sickle cell disease is widely variable, ranging from a mild, asymptomatic course with survival into the sixth or seventh decade to a very severe course with multi-organ damage and early mortality [ 1 ] . Some of the genetic factors contributing to this phenotypic diversity (particularly those linked to the globin genes, i.e. α-thalassemia and β-globin gene cluster haplotypes) have been well recognized [ 2 ] .
In younger asymptomatic women, we also collected biopsy samples of ectocervix and endometrium from hysterectomy specimens.
The prevalence of CD in the US is 1:250 [ 1 ] and the ratio of symptomatic to asymptomatic cases is between 1:5 and 1:7 [ 2 ] . Before the advent of serological testing for diagnosing CD, it was considered a rare disease in the US.
At the present time, the T3197C nucleotide substitution is considered a polymorphism and it is not thought to have pathogenic significance by itself [ 31 ] . Although most pathogenic mutations are heteroplasmic, many homoplasmic mutations have been reported to have synergistic effects in the presence of other primary mutations [ 32 33 ] . The only difference in mtDNA between the affected child and the asymptomatic mother is the A189G mutation in the hypervariable D-loop region.
In an alternative “mixed ART effects” scenario, less optimistic assumptions were made: that treatment reduces transmissibility only to the same levels as in asymptomatic infected individuals (two-thirds reduction from no treatment), and that behavior in treated patients is the same as in other adults.
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