Words similar to aspirin
Example sentences for: aspirin
How can you use “aspirin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Table 3displays the association between aspirin use and lung cancer risk in the total sample, as well as among females and males separately.
Armed with such evidence—whether it qualifies aspirin as “proven therapy” is open to subjective interpretation—many placebo opponents, we maintain, would argue for an active-controlled design as a more ethical alternative to the placebo-controlled design actually used in APPROVe [11].
These agents address the different physiologic roles of the two COX enzymes as well as reduce adverse side effects of prolonged drug use [ 37 ] . Nevertheless, as discussed above, certain experimental and population studies [ 20 21 22 ] do indicate that drugs like aspirin, which can act on both COX-1 and 2, may play a role in prevention and therapy of pancreatic cancer.
The second set of analyses (fully adjusted) were adjusted for all covariates and potential confounders: age, sex, race, poverty to income ratio, body mass index, prevalent cardiovascular disease, prevalent diabetes, prevalent chronic inflammatory condition, current acute illness, and use of alcohol, non-steroidal anti-inflammatory medication, aspirin, and estrogen replacement.
The cyclooxygenase pathway and NSAIDs have been implicated in pancreatic carcinogenesis, as elevated levels of COX-2 mRNA and protein have been detected in pancreatic carcinomas relative to histologically normal cells [ 14 15 16 17 18 19 ] . Further, both aspirin [ 20 21 22 ] and other NSAIDs [ 19 ] have been shown to inhibit pancreatic cancer cell proliferation and induce apoptosis in vitro . Recent studies have also reported an association between oncogenic ras and COX-2 expression [ 23 24 ] . Since pancreatic tumors tend to exhibit a high frequency of K- ras mutations [ 25 ] , the relationship between the K- ras oncogene and COX-2 should be explored further in vivo.
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