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Example sentences for: asbt

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To determine if non-liver derived cells also posses differential sensitivity to bile acid-induced cytotoxicity, we engineered CHO cells to take up bile acids actively by expressing asbt.
Furthermore, it was possible to chase the incorporated radiolabeled TCA from CHO.asbt.
As shown in Figure 8, PI3K activity in response to TCA or GCDCA was not evident in CHO.asbt.
Analysis of total RNA from the selected clones (CHO.asbt) readily showed the presence of the recombinant asbt mRNA (Figure 3A).
Bile acids are reclaimed from the lumen of the intestine and returned to the liver via portal blood for reuse [ 1 ] . The recovery of bile acids from the intestine is an efficient process that involves both passive transport along the entire axis of the intestine, and active transport in the terminal ileum [ 5 ] . The apical sodium/bile acid co-transporter (asbt) mediates the active uptake of conjugated bile acids in the ileum [ 5 6 ] . In hepatocytes, both sodium-dependent and sodium-independent transport systems on the sinusoidal membranes extract bile acids from portal blood.