Words similar to aryl
Example sentences for: aryl
How can you use “aryl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Mefloquine is an aryl amino alcohol which accumulates in both the liver and the lungs, and is subject to enterohepatic circulation.
Analysis of biophores #1, #2 (#4, #5) showed that both of them occur in substituted 5-[4-(benzyloxy) phenyl]-1,3,4-oxadiazol-2-(3H)-ones and their analogs (Figure 1), many of which are known to be strong MAO-B inhibitors [ 9 ] . Biophore #2 represents a flexible -CH 2 O- bridge between aryl moieties and was found to enhance the activity and selectivity of the inhibitors as shown in the original work [ 9 ] . Biophores #1 and #2 include aromatic moieties, whose main function is presumably to bind to the hydrophobic site of MAO.
Thus the aryl ring (Figure 2B) can carry quite a large variety of substituents that enhance binding if they are hydrophobic [ 21 ] . Since many good biophores were identified in the DA database we designed two different DA precursors (Figure 5) instead of one.
Biophore #3 (#6) exists in N-(2-Aminoethyl)-benzamides with substitutions on the aryl ring.
They include: (1) sulfate esters of polysaccharides {carrageenan [ 1 16 17 18 19 ] , cellulose sulfate [ 12 13 14 15 ] , and dextran or dextrin sulfate [ 1 2 3 4 5 6 7 8 9 10 11 ] }; (2) aryl sulfonates {poly(naphthalene sulfonate) [ 22 23 24 ] and poly(styrene-4-sulfonate) [ 20 21 ] }; and (3) aliphatic {Carbomer 974P/BufferGel [ 25 26 27 28 29 ] } and aromatic carboxylates {CAP [ 30 31 32 33 34 35 36 37 ] }. The anti-HIV-1 properties of these polymers are expected to depend on their complexation with virus proteins which is likely to occur mainly through the formation of salt linkages or ion pairs between oppositely charged groups on the polymers and virus proteins, respectively [ 56 ] . However, the anti-HIV-1 properties of these polymers may depend not only on their charge density, but also on the characteristics of their uncharged portions, which may be involved in hydrophobic and hydrogen bonding interactions which can elicit profound conformational changes in hydrophobic regions of proteins and cause disassembly of complex proteins consisting of subunits [ 57 ] . For these reasons it is not be expected that all anionic polymers, considered as anti-HIV-1 microbicides, would have similar biological activities.
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