Words similar to arrhythmic
Example sentences for: arrhythmic
How can you use “arrhythmic” in a sentence? Here are some example sentences to help you improve your vocabulary:
As shown in Table 1we applied Autocorrelation, MESA and the "Chi-squared Periodogram" [ 57 ] to locomotor activity data generated by individuals who were either wild-type, cyc 01/+, cyc 02/+, or who had only one copy of the cyc locus ( cyc -deletion/+) [ 58 ] . We advocate using these methods simultaneously to maximize accuracy (for example, if Autocorrelation analysis indicates that a signal is arrhythmic we reject any value from MESA because MESA does not evaluate rhythmicity and will return an estimate for any signal).
Upon release into constant darkness cry1,2 -/-mice immediately become arrhythmic at the behavioral level [ 22 23 ] , at the level of SCN electrophysiology [ 28 ] , and at the cellular/molecular level [ 23 ] . Of the available mouse models for circadian dysfunction, only per1,2 double mutant mice [ 29 ] , bmal1 knockout mice [ 30 ] , and mice with an ablation of the SCN [ 31 ] show a similarly dramatic phenotype.
Such concerns motivated us to develop a set of tools for the analysis of circadian rhythms [ 27 ] . Here we apply two key features of this analytic package that were unavailable for our earlier report on the effects of cry b in the periphery [ 23 ] . First is a method to eliminate nonlinear trends in the data, a potential source of artifact that could affect whether luciferase activity is scored as rhythmic or arrhythmic.
The appearance of rhythmicity in the correlogram is applied as a qualitative criterion so that we do not treat weakly rhythmic data as arrhythmic data.
These findings in cry1,2 -/-mice contrast with the findings of sleep studies in animals that are rendered arrhythmic by lesioning of the SCN.
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