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Example sentences for: argos

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We have demonstrated, in the case of body patterning in the Drosophila embryo, that our algorithms allow the genome-wide identification of regulatory modules when the motifs for the transcription factors are known (algorithm Ahab), or when only related modules are known (customized Gibbs sampler in conjunction with Ahab), or when only genomic sequence is analyzed with Argos.
We evaluated the results of Argos for the the modules in additional File 1. Log probability scores > 70 were taken as significant, since they are found very rarely using randomized noncoding sequence 1. With this threshold and at least l00 bp overlap, half of the modules were recovered, indicating a 50% false negative rate.
Our algorithm Argos for predicting enhancers from raw genomic sequence works astonishingly well.
Argos is the first successful attempt to predict regulatory modules using only the genome without training data.
Namely, following the hierarchical structure in Figure 1, Argos could be used to predict modules, then the customized Gibbs sampler to predict binding sites (weight matrices) and finally Ahab to predict, genome wide, genes in the same regulatory network.