Words similar to appending
Example sentences for: appending
How can you use “appending” in a sentence? Here are some example sentences to help you improve your vocabulary:
Data annotation involves appending descriptive information to experimental data with the intention of creating an encapsulated data object that can be intelligently connected to related data in other databases.
The pre-insertion locus of each L1 was recreated by collecting 50 nucleotides upstream and downstream from the 5' and 3' TSDs, respectively, and appending them to the TSD sequence.
Again, appending amino acids 1-125 to this mutant restored G1 prolongation (A126-153), as did amino acids 1-97 (A 98-153).
For example, Herschlag and co-workers have previously shown that a nucleobase could complement an abasic site within the hammerhead ribozyme, restoring cleavage activity [ 1 ] . Similarly, Porta and Lizardi engineered a hammerhead ribozyme that assumed an inactive secondary structure; upon the addition of an oligonucleotide that disrupted the engineered secondary structure, the ribozyme was activated [ 2 ] . More recently, it has previously been shown that many selected nucleic acid binding species (aptamers) undergo conformational changes upon ligand binding [ 3 4 5 6 ] In addition, when aptamers are conjoined to ribozymes, the ligand-induced conformational changes in the aptamers frequently modulate the structures and hence the activities of the ribozymes [ 7 8 9 ] For example, binding of theophylline to the anti-theophylline aptamer [ 10 ] modulates the conformation of residue [ 11 12 ] and the overall stability of the aptamer [ 10 13 ] . Appending the anti-theophylline aptamer to the hammerhead ribozyme allowed cleavage activity to be modulated by 110-fold by theophylline [ 13 ] . Similarly, appending the anti-theophylline aptamer to a small ribozyme ligase (L1) generated an aptazyme that was activated 1,600-fold by saturating theophylline concentrations [ 14 ] .
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