Words similar to apobec
Example sentences for: apobec
How can you use “apobec” in a sentence? Here are some example sentences to help you improve your vocabulary:
In particular, APOBEC3G targets the reverse transcription step of the HIV life cycle, in which the viral genomic RNA is converted into proviral DNA, which is then integrated into the host genome (Mangeat et al.
The anti-HIV properties of APOBEC3G were discovered because most viral strains escape its neutralising properties.
Although there is still some debate over exactly how APOBEC3G leads to viral eradication, the most likely scenario is that G3A hypermutation results in the generation and incorporation of a multitude of deleterious mutations that fatally disrupt viral functions.
This case is especially striking because rather than killing pathogens through protein or cellular interactions, like most immune genes, APOBEC3G works by manipulating the genome sequence of the invading microbe.
Less clear is whether other host proteins act in the same manner as APOBEC3G.
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