Words similar to apobec
Example sentences for: apobec
How can you use “apobec” in a sentence? Here are some example sentences to help you improve your vocabulary:
Furthermore, because positive selection on APOBEC3G has operated for at least 30 million years and lentiviruses in general, and HIV in particular, are likely to be more recently evolved than this, it is clear that a broad range of retroviral pathogens have been responsible for the adaptive evolution of this particular immune gene (Sawyer et al.
By increasing the rate at which deleterious mutations appear, APOBEC3G pushes viruses over this edge, causing a form of ‘lethal mutagenesis’ that results in their destruction; the rate of mutation becomes so high that no genome can reproduce itself faithfully, and the population crashes.
The genomes of primates contain a family of nine APOBEC genes that encode enzymes involved in the editing of RNA and/or DNA through the deamination of cytosine (C), so that this nucleotide mutates to uracil (U).
Less clear is whether other host proteins act in the same manner as APOBEC3G.
The anti-HIV properties of APOBEC3G were discovered because most viral strains escape its neutralising properties.