Example sentences for: apical

How can you use “apical” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the CFTR chloride channel [ 1 ] . CFTR is known to possess multiple cellular functions beyond its role as an apical membrane chloride channel [ 2 ] . For example, regulation of other ion channels, such as the epithelial sodium channel and the outwardly rectified chloride channel, are well-described functions of CFTR [ 3 4 ] . Numerous other functions, such as regulation of intracellular vesicular pH, regulation of membrane recycling, and regulation of mucin exocytosis are less firmly established.

  • Caco-2 cells were grown as confluent monolayers on transwell filters and tight-junction formation was confirmed by the inability of inulin to diffuse from the apical to the basolateral surface.

  • The apical areas are where type II pneumocytes are located, and the very distal parts of the respiratory tree are where Clara cells are located.

  • The oligonucleotide used for these studies contains the apical portion and part of the stem portion of domain III and, therefore, might bind one or both of these subunits.

  • The result is that, when the frequency of sound is high, it will produce a peak of vibration near the oval window (Figure 1A); if the frequency is low, the peak of vibration will be nearer the far (apical) end of the cochlea [10].


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