Words similar to ap-
Example sentences for: ap-
How can you use “ap-” in a sentence? Here are some example sentences to help you improve your vocabulary:
This cohort of AP-1, Fos, and ets family members may also preferentially bind to different AP-1 sites in MMP promoters, with subtle effects on gene expression [ 32].
Both ERs enhance transcription from genes with classical estrogen response elements (EREs), but ERα requires less ligand to obtain maximal activation than ERβ [ 25 26 ] . Likewise, both ERs suppress the activity of the TNFα promoter in response to estrogens, but ERβ is a more potent repressor than ERα [ 27 ] . However, some of the most striking isoform-specific differences in gene regulation are observed at promoters, such as that of cyclin D1, which contain AP-1 sites or related cyclic AMP response elements (CREs).
From DNase I footprinting studies (Figure 2and data not shown) we conclude that recombinant HA-NFATp binds DNA both on its own and in cooperation with AP-1 proteins (cJun/cFos and cJun/cJun).
Activation of the JNK pathway can lead to the phosphorylation of downstream members including c-jun that belongs to the AP-1 transcription factor family [ 12 52 ] . Because results from this study indicated that JNK pathway was activated by 25-OH-cholesterol, one could expect that AP-1 would be activated in cells treated with cholesterol oxides.
15d-PGJ 2 , 15-deoxy-delta 12, 14-PGJ 2 ; AP-1, activator protein-1; ERK, p42/44, Extracellular signal-Regulated Kinase; LDL, low density lipoprotein; MAP kinases, Mitogen-Activated Protein kinases; MTT (3-(4,5-dimethylthiazole-2yl)-2,5-diphenyltetrazolium bromide); PCD, programmed cell death; PPARs, peroxisome proliferator-activated receptors; SAPK/JNK, Stress-Activated Protein Kinase/ c-Jun NH2-terminal Kinase.
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