Example sentences for: aortic

How can you use “aortic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cardiovascular features included aortic dilatation in mid-life, one case of dissection at age 56 yr, and a high frequency of mitral valve prolapse associated with arrhythmia.

  • In 1993, a postmortem left pneumonectomy was performed in a 65-year-old man who died from acute respiratory distress syndrome complicating postoperative bronchopneumonia 5 days after surgical resection of a thoracoabdominal aortic aneurysm.

  • Initial reports of remarkably high prevalence of aortic and mitral regurgitation (AR and MR) as assessed by echocardiography in five separate populations [ 2 ] were subsequently supported by most [ 3 4 5 ] but not all investigators [ 6 ] . These uncontrolled reports were soon followed by a series of studies in which prevalence of echocardiographically-defined AR and MR were assessed in persons who had taken fenfluramine, dexfenfluramine, phentermine, or combinations of these medications and compared to unexposed, matched control populations [ 7 8 9 10 11 12 13 14 15 ] . The most recent of these studies found 30% of persons currently taking fenfluramine or dexfenfluramine had mild or greater AR or moderate or greater MR, similar to the very high prevalence reported in older studies [ 15 ] . The only prospective study found a significant, exposure-related increase in the risk of clinically diagnosed valve disease among users of fenfluramine and dexfenfluramine, but not phentermine [ 16 ] .

  • These findings lend strong support to the view that fenfluramine and dexfenfluramine are potent causal factors in the development of both aortic and mitral valvular heart disease.

  • The study showed that the adaptive enlargement was associated with increased gene expression of TGF-β1 and β3, known as tissue remodeling mediators [ 12 17 29 ] . Gene expression of TGF-β1 and β3 was upregulated at 1 and 3 days and 1 week upon increase in blood flow, while the flow-induced aortic enlargement occurred 2 weeks after ACF creation.


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