Words similar to anticonvulsant
Example sentences for: anticonvulsant
How can you use “anticonvulsant” in a sentence? Here are some example sentences to help you improve your vocabulary:
At anticonvulsant doses, carbenoxolone produced a hypnotic effect in the pentobarbitone sleep test and motor impairment in the rotarod test, but only at a dose of (400 mg/kg), which had anticonvulsant effect, did carbenoxolone show muscle relaxant activity in the traction test.
These could explain the anticonvulsant, muscle relaxant and hypnotic effects of carbenoxolone.
Preliminary reports have linked ligands active at the GABA receptor with SB or other NTDs, including benzodiazepines, alcohol, and zinc [ 7 8 9 10 11 ] . Preliminary work from this laboratory has shown the GABAa receptor agonist muscimol and the GABAb agonist baclofen produce both SB and the Arnold-Chiari malformation, commonly associated with SB [ 12 13 14 ] . VA appears to produce most of its anticonvulsant effects by increasing levels of GABA in the CNS, presumably by inhibiting the enzyme GABA-transaminase (GABA-T).
Thus, we considered the possible anticonvulsant effect of carbenoxolone in animal seizure models.
It is known that many neuroactive steroids have anticonvulsant activity [ 27], and during ethanol withdrawal the B6 and D2 mice have differential sensitivity to the anticonvulsant effects of allopregnanolone [ 28].
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