Example sentences for: anticonvulsant

How can you use “anticonvulsant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • At anticonvulsant doses, carbenoxolone produced a hypnotic effect in the pentobarbitone sleep test and motor impairment in the rotarod test, but only at a dose of (400 mg/kg), which had anticonvulsant effect, did carbenoxolone show muscle relaxant activity in the traction test.

  • These could explain the anticonvulsant, muscle relaxant and hypnotic effects of carbenoxolone.

  • Preliminary reports have linked ligands active at the GABA receptor with SB or other NTDs, including benzodiazepines, alcohol, and zinc [ 7 8 9 10 11 ] . Preliminary work from this laboratory has shown the GABAa receptor agonist muscimol and the GABAb agonist baclofen produce both SB and the Arnold-Chiari malformation, commonly associated with SB [ 12 13 14 ] . VA appears to produce most of its anticonvulsant effects by increasing levels of GABA in the CNS, presumably by inhibiting the enzyme GABA-transaminase (GABA-T).

  • Thus, we considered the possible anticonvulsant effect of carbenoxolone in animal seizure models.

  • It is known that many neuroactive steroids have anticonvulsant activity [ 27], and during ethanol withdrawal the B6 and D2 mice have differential sensitivity to the anticonvulsant effects of allopregnanolone [ 28].


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