Words similar to anti-tumor
Example sentences for: anti-tumor
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Overall, clones generated from endogenous anti-tumor responses had higher RE for the native peptide than clones generated from post-vaccine responses (Figure 5C and 5D).
Although the etiologies and pathologies of RA and OA differ, it is clear that in both of these diseases pro-inflammatory cytokines are present, resulting in an inflammatory state as well as cartilage degradation [ 14 ] . As further evidence for the role of pro-inflammatory cytokines in RA, anti-tumor necrosis factor-α (anti-TNF-α) and anti-interleukin 1 (anti-IL-1) therapies can reduce inflammation and retard the progression of disease as assessed radiographically [ 15 16 ] . However, side-effects with these approaches, such as the development of lymphomas in patients using anti-TNF-α therapies, demonstrate that alternative therapies are needed [ 17 ] .
IP-10/CXCL10, MIG/CXCL9 and IFNγ are known to have potent anti-tumor activities in vivo [ 14 15 16 17 ] . Both MIG/CXCL9 and IP-10/CXCL10 are important for the anti-tumor activity mediated by IFNγ inducing cytokines such as IL-12 [ 16 18 19 ] . Based on these findings we hypothesized that augmentation in IFNγ, MIG/CXCL9, and IP-10/CXCL10 would play an important role in the SLC/CCL21-mediated anti-tumor response.
Potentiation of the anti-tumor activity of 5-FU by methotrexate (MTX) and leucovorin (LV) requires careful scheduling to achieve the most favorable interactions between these 3 drugs.
To address this important issue, we undertook a systematic examination of the complexity of T cell responses induced by heteroclitic peptide vaccination, and compared these responses to endogenous anti-tumor T cell responses which develop in some patients.
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