Words similar to anti-osteoclastogenic
Example sentences for: anti-osteoclastogenic
How can you use “anti-osteoclastogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results imply a model for arthritic joints in which macrophage precursors entering an inflamed joint are exposed to RANKL and are subsequently rendered resistant to the anti-osteoclastogenic effects of IFN-γ expressed by activated T cells in the synovium.
The resolution of this issue is further clouded by the apparent contradictory findings that IFN-γ is an extremely potent anti-osteoclastogenic factor [ 38 ] but it can be found at high levels in sites of osteolysis [ 39 ] . To reconcile this controversy we performed a series of experiments aimed at understanding how IFN-γ could induce either bactericidal effects via macrophage activation or osteoclastic bone resorption, by influencing the same progenitor cell in the same bone environment.
There are situations, however, in which the anti-osteoclastogenic effects of IFN-γ are not so clear.
RANKL-pretreated RAW cells are resistant to the anti-osteoclastogenic effect of IFN-γ
Furthermore, several clinical studies have failed to demonstrate efficacy of IFN-γ administration as an anti-osteoclastogenic agent to prevent bone loss [ 28 29 30 ] . There seem to be situations in which IFN-γ does not act as an anti-osteoclastogenic agent.