Words similar to anthranilate
Example sentences for: anthranilate
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Subunits for a given reaction are named at the same hierarchical level: anthranilate synthase (first reaction) consists of TrpAa and TrpAb, and tryptophan synthase (fifth reaction) consists of TrpEa and TrpEb.
Because acl is tightly organized with trpAa and trpAb , it seems feasible that anthranilate might be the substrate of acl . An anthranilate-CoA ligase has been described recently in Azoarcus evansii by Schuhle et al . [ 33].
The aromatic ring is highly stable, and CoA thioesterification can provide chemical activation, allowing cleavage of the aromatic ring, as exemplified by catabolism of benzoate, 4-hydroxybenzoate, and anthranilate [ 32].
A rationale for inclusion of kprS and kynU in the C. psittaci tryptophan operon can be visualized from an examination of Figure 2. The ability of C. psittaci to synthesize L-tryptophan requires an alternative source of anthranilate (other than chorismate) as C. psittaci lacks anthranilate synthase.
Within the low-GC block, trpR is separated by four ORFs from genes encoding the two subunits of anthranilate synthase ( trpAa and trpAb ). These probably do not function for general tryptophan biosynthesis since paralogs of these genes, which exhibit a phylogenetically congruent context of gene organization, exist elsewhere in the genome (Figure 6).