Words similar to aneuploidy
Example sentences for: aneuploidy
How can you use “aneuploidy” in a sentence? Here are some example sentences to help you improve your vocabulary:
PCS of homologues during meiosis I and equational division of sister chromatids during anaphase I [ 56 57 ] and premature separation of chromatids during meiosis II [ 58 59 ] and mitosis [ 60 61 ] have been shown to increase the incidence of aneuploidy in subsequent divisions.
Based on studies involving compounds that alter microtubular kinetics and induce both cell-cycle delay and aneuploidy, several groups have proposed that temporal perturbations during mammalian oocyte maturation (OM) predispose oocytes to aneuploidy [ 3 4 5 6 ] . In addition to faulty microtubule kinetics, perturbations during OM may also stem from abnormal function of centrosomes, kinetochores, spindle checkpoints proteins, the anaphase-promoting complex (APC), the securin-separin-cohesion complex proteins, and the proteasome [ 7 ] .
The frequencies of hyperploid cells were used as a measure of aneuploidy because an unknown proportion of the hypoploid cells is influenced by technical artifact resulting from excessive chromosome scatter during slide preparation.
Although numerous hypotheses have been proposed to describe the etiology of aneuploidy in human gametes, the only steadfast association remains maternal age [ 1 2 ] . Besides this association, very little information is available about the numerous potential mechanisms that may disrupt normal chromosome segregation in oocytes.
However, the most obvious models for the deleterious effects of aneuploidy should instead depend on the total number of genes.
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