Example sentences for: anabolic

How can you use “anabolic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The only bone anabolic agent known to increase bone mineral density in both animal models and clinical settings is human parathyroid hormone 1-34 (PTH), which has recently been approved by the FDA in patients with advance osteoporosis [ 10 ] . Bone-related basic and clinical research has been searching intensively for alternative anabolic agents for the treatment of osteoporosis.

  • Although the molecular signaling mechanisms that transduce the effects of phasic patterns of work activity to modify muscle mass are incompletely understood, recent evidence implicates pathways that include the signaling molecules PI3 kinase, Akt, mTOR, S6K, and ERK, the ubiquitin ligases MAFbx and MuRF1, and transcription factors of the FOX superfamily in the control of both catabolic and anabolic processes [21,22,23,24].

  • Metastatic bone cancer will also affect the balance between the anabolic and catabolic processes at the local site of invasion.

  • Collagen and CTX fragments will rearrange with age to three age-modified forms: the isomerised form ( L-isoaspartyl peptide [β L]), where the bond between the aspartic acid and glycine residue goes through the β-carboxyl group of the aspartyl residue; the racemised form ( D-aspartyl peptide [α D]), where the aspartic acid (D 1211) is on a D-enantiomeric form; and the isomerised and racemised form ( D-isoaspartyl peptide [β D]) [ 9 ] . The relative accumulation of the three age-modified forms is dependent on the balance between anabolic and catabolic processes in bone, and pathologic situations affecting these processes may thus also affect the relative amounts of the four CTX forms [ 9 10 11 ] .

  • Such a decrease in collagen type I half-life is likely to reflect a significant imbalance between anabolic and catabolic processes at the focal area of metastatic invasion [ 11 ] .

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