Words similar to aml

Example sentences for: aml

How can you use “aml” in a sentence? Here are some example sentences to help you improve your vocabulary:

The proto-oncogene TEL (Translocation, Ets, Leukemia) is a transcriptional repressor that contains a C-terminal Ets family DNA binding domain; a central domain that together with co-repressors recruit histone deacetylases [ 1 2 3 ] ; and an N-terminal SAM (sterile, alpha, motif) domain [ 4 5 6 ] , which we have recently shown forms a polymer [ 7 ] . Chromosomal translocations in a variety of leukemias result in fusion of the SAM domain of TEL to tyrosine kinase domains such as ABL, PDGFβ and JAK2 [ 8 9 10 11 12 13 14 ] or to the transcriptional activators AML1 and ARNT [ 15 16 17 ] . In the tyrosine kinase fusions, SAM domain polymerization leads to constitutive activation of the tyrosine kinase domains, which leads in turn to cell transformation [ 10 12 18 19 ] . Thus, compounds that block TEL-SAM polymerization could be effective in treating these leukemias.
Four patients were enrolled with AML refractory to previous induction therapy, and 10 were enrolled with relapsed AML.
For K = 2, eight ALL T-cell observations are misclassified with the AML observations.
(7) Golub et al . [ 12 ] wished to be able to distinguish acute myeloid leukemia (AML) from acute lymphoblastic leukemia (ALL).
From these two plots, we conclude that the gene expression levels of most of the genes (genes with 99% confidence intervals containing zero) are not significantly different in both AML and ALL samples.