Example sentences for: aminosalicylic

How can you use “aminosalicylic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have also demonstrated that mesalamine (5-aminosalicylic acid), used as a frontline treatment for inflammatory bowel disease, could prevent apoptotic epithelial cell death in response to peroxynitrite [ 14 ] . Peroxynitrite is a potent oxidant; formed from two free radicals - nitric oxide and superoxide - that catalyzes the nitration of tyrosine residues.

  • Sulfasalazine is a widely used anti-inflammatory agent in the treatment of Crohn's disease and ulcerative colitis [ 1 2 3 ] . Recent data has demonstrated that SSZ is also safe and effective in the treatment of rheumatoid arthritis and other rheumatological disorders [ 4 5 ] . Sulfasalazine is a dimer composed of 5-aminosalicylic acid linked by an azo bond to sulfapyridine.

  • The anti-inflammatory activity of SSZ is due to the 5-aminosalicylic acid component while the majority of the adverse side effects have been attributed to the sulfapyridine moiety [ 14 15 16 ] . Fever, abdominal pain, and rash may develop in 3% to 20% of treated patients, but these side effects are usually mild and improve with dose reduction [ 7 11 12 ] . Severe side effects necessitating SSZ discontinuation occur in less than 5% of treated patients [ 11 ] .


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