Example sentences for: amide

How can you use “amide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • GSPS is a bifunctional enzyme: its synthase domain carries out the ATP-dependent fusion of two glutathione moieties to the polyamine spermidine to form the antioxidant metabolite GSP, while its amidase domain hydrolyzes the amide linkage to release glutathione and spermidine [ 26, 55, 56].

  • It is unlikely that γ-Glu-Cys would have been available because formation of the high-energy amide bond would be unlikely to occur abiotically.

  • As GshA has a binding site that accommodates γ-Glu-Cys, it would appear to be an ideal progenitor of GshB, which uses γ-Glu-Cys as a substrate and also catalyzes the ATP-dependent formation of an amide bond.

  • Less strong Lewis bases are the charge-compensated Glu in an ion-pair with Arg, the amide group of Gln and Asn, and finally the carbonyl of the peptide backbone as the weakest [ 29 ] . The importance of the ligand was demonstrated by substitution of His with the weaker Lewis base Asn in the apoprotein of the bacterial light-harvesting complex LH1, which eliminated assembly of the complex in vivo and reconstitution in vitro [ 30 ] . Formation of a stable coordination bond with a weaker Lewis base is expected to require a stronger Lewis acid.

  • 3) It displays an amide group that occupies a cavity not filled by nicotine or acetylcholine, and makes a network of hydrogen bonds with the indole nitrogen of alpha4-Trp182, the backbone carbonyl of beta2-Ser133 and beta2-Phe144, and with the backbone nitrogen of beta2-Leu146 (Figure 5B).


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