Example sentences for: amelioration

How can you use “amelioration” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 5B) would be expected to lead to significant amelioration of obese phenotypes, consistent with effects of adrenalectomy on other forms of obesity [ 3 4 5 6 7 ] . Indeed adrenalectomy initially led to a greater loss of body weight after surgery in the diet-induced obese mice (results in text above).

  • Some of the original place names were rather crude and had to be changed to appeal to more genteel tastes, but such amelioration was sporadic.

  • Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.

  • However, analyses in which synteny and phylogenetic information were also considered suggest that codon bias and G+C content are poor indicators of HGT [ 45 ] . A role for 'amelioration', whereby structural characteristics of the foreign gene are eventually homogenized to resemble those of the recipient species, has been assumed, but the rate was postulated to be the same as the rate of random, forward mutation [ 42 ] . In addition to alterations in codon usage (as reflected in G+C content), for a bacterial gene to function efficiently in a nematode presumably requires acquisition of regulatory elements (including a promoter) and structural elements (including a poly(A) tail and, optionally, a trans -spliced leader).

  • Whatever small faults he could and did find with America, he endlessly reminded anyone who listened that the best achievement of mankind was America, whose current failings were trivial by historic standards, which was in a constant process of amelioration, and which offered its citizens the best chance in history for a good life.


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