Example sentences for: allergen

How can you use “allergen” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The downregulation of SLAM gene expression observed here after allergen challenge, which induces a Th2 response, is consistent with this earlier observation.

  • 5-fold of the normal control level); induction of only a limited set of genes by this allergen, as its inhalation causes an acute inflammation response mainly in airways; and the use of probes from whole-lung homogenates, which may result in a dilution of signals, making it difficult to detect genes induced only in the airways.

  • For instance, the EF-hand protein identified as having a pollen allergen Bra r II domain is similar to an EF-hand protein from pollen (APC1) isolated by Rozwadowski et al.

  • Cigarette smoke has also been considered a major player in the pathogenesis of asthma and as a trigger for acute symptoms [ 2 ] . Exposure to cigarette smoke activates an inflammatory cascade in the airway epithelium resulting in the production of a number of potent cytokines and chemokines, with accompanying damage to the lung epithelium, increased permeability, and recruitment of macrophages and neutrophils to the airway [ 3 ] . Even brief exposure to cigarette smoke has been shown to increase expression of IL-8 in primary cultures of human bronchial epithelial cells (HBEs) in the presence of dust mite allergen [ 4 ] . Increased release of the chemokine IL-8 has also been shown for cultured HBEs exposed to cigarette smoke extract (CSE) [ 5 6 ] and diesel exhaust particles [ 7 ] . However, the precise molecular events that bring about these intracellular changes and acute inflammation in lung epithelial cells are not well understood.

  • In keeping with this, IgE antibody responses to cat allergen are not quantitatively as high as those to dust mites [17].


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