Words similar to allergen
Example sentences for: allergen
How can you use “allergen” in a sentence? Here are some example sentences to help you improve your vocabulary:
The allergic cynomolgus monkey ( Macaca fascicularis ) has been used as a non-human primate model to study inflammatory responses in the lung following allergen challenge [ 12, 13].
Homes in Sweden, Berlin, the United Kingdom, and New Zealand have progressively higher concentrations of mite allergen and progressively higher prevalence of sensitization to mite allergens [7].
The use of a higher criterion (that is, threefold) excluded some genes, such as those for MCP-1 and ICAM-1, which are known to be regulated in the acute phase of allergen challenge [ 15, 16]; on the other hand, a lower criterion, such as twofold, increased the probability of false-positive genes and lack of confirmation by RT-PCR (see Validation of the microarray gene expression, below).
Cigarette smoke has also been considered a major player in the pathogenesis of asthma and as a trigger for acute symptoms [ 2 ] . Exposure to cigarette smoke activates an inflammatory cascade in the airway epithelium resulting in the production of a number of potent cytokines and chemokines, with accompanying damage to the lung epithelium, increased permeability, and recruitment of macrophages and neutrophils to the airway [ 3 ] . Even brief exposure to cigarette smoke has been shown to increase expression of IL-8 in primary cultures of human bronchial epithelial cells (HBEs) in the presence of dust mite allergen [ 4 ] . Increased release of the chemokine IL-8 has also been shown for cultured HBEs exposed to cigarette smoke extract (CSE) [ 5 6 ] and diesel exhaust particles [ 7 ] . However, the precise molecular events that bring about these intracellular changes and acute inflammation in lung epithelial cells are not well understood.
Enzymatic activity has been implicated as a source of the allergenic property of Der p1, the major dust mite allergen [ 30 31 32 ] . In order to account for this variable, the enzymatic activity of the variant protease GP002 was compared BPN' Y217L.
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