Words similar to alkb
Example sentences for: alkb
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The Non-redundant Protein Sequence Database (NCBI) [ 21] was searched using the PSI-BLAST program [ 22] run to convergence, with a profile-inclusion threshold of 0.01 and AlkB protein sequences from various organisms as queries.
In addition to the AlkB orthologs, these searches retrieved from the database, with statistically significant expectation (e) values, several other more distant homologs of AlkB, including uncharacterized eukaryotic proteins and fragments of the polyproteins of plant RNA viruses from the caria-, tricho- and potexvirus families.
These reactions are consistent with the observation that, unlike AlkA, AlkB has no DNA glycosylase activity [ 18].
AlkB is widely represented in bacteria and eukaryotes and has an important role in countering the toxic DNA modifications caused by alkylating agents in both
The connection between nucleic acid methylation and the AlkB homologs described here is supported by the domain architecture of a conserved pair of animal proteins (C14B1.
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