Example sentences for: alkb

How can you use “alkb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition to the AlkB orthologs, these searches retrieved from the database, with statistically significant expectation (e) values, several other more distant homologs of AlkB, including uncharacterized eukaryotic proteins and fragments of the polyproteins of plant RNA viruses from the caria-, tricho- and potexvirus families.

  • The clavaminic acid synthase, an outlier of this latter family, has its own characteristic inserts, including a giant (approximately 70 amino acids) insert between strands 4 and 5 [ 8], and some members of the AlkB family have smaller inserts in the same position (Figure 1).

  • The conservation of all the residues implicated in catalysis in the biochemically uncharacterized proteins such as AlkB, EGL-9, leprecan and YbiX suggests they all catalyze oxidative reactions similar to those catalyzed by IPNS, DAOCS, CAS and related enzymes such as protein lysyl/prolyl hydroxylases, EFE and leucoanthocyanidin oxidases [ 1, 2].

  • The predicted 2OG-Fe(II) dioxygenase activity of AlkB is probably involved in the detoxification of methylated bases in ssDNA, possibly through hydroxylation of the methyl groups, resulting in less toxic base derivatives.

  • The most intriguing finding made during our analysis of the AlkB family is the existence of multiple eukaryotic AlkB homologs, other than the actual orthologs, especially in plants and their viruses.


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