Words similar to aldh

Example sentences for: aldh

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Previous reports of HPLC assays for ALDH reactions with tissue extracts used a single time point at 60 min to measure accumulation of product, after documenting that retinoic acid formation was still linear in time course experiments [ 33 ] . In our hands, the reaction with purified enzyme was only linear for product formation up to 10-15 minutes.
In addition, our results indicate that in HL60 cells, the prototype cell line for studying retinoic acid induced cell differentiation, ALDH1A1 is not the operative oxidizing enzyme for retinal.
The IC 50 values for mouse ALDH1A1 are between the values observed with propanal (0.
In this paper we show that DPAB is a potent inhibitor of retinal oxidation by murine and human ALDH1A1.
The development of inhibitors which can target individual ALDH enzymes provides one approach for addressing the role of a specific ALDH enzyme in the oxidation of retinal to retinoic acid in a given cell type.