Words similar to aldh

Example sentences for: aldh

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In one report, ALDH1A1 protein was not detected by Western blot, but enzyme activity was detected using flow cytometry and a fluorescent aldehyde substrate [ 5 ] . In a second study, ALDH1A1 protein was detected using an ELISA assay and activity was detected using aldophosphamide as substrate [ 31 ] . In these two studies, designed to look at the relationship of ALDH1A1 activity to antitumor drug resistance, the levels of ALDH1A1 were low in HL-60 compared to other cell types, corresponding to the sensitivity of HL-60 cells to oxazaphosphorines.
Although DPAB is a more potent inhibitor of human ALDH1A1 than DEAB, we were concerned that DPAB was not remaining in solution at 50 μM in the culture media.
In vivo , the introduction of ALDH1A1 mRNA into Xenopus embryos induces early synthesis of retinoic acid, while ALDH1A1 expression is detected during the tail bud stages of Xenopus embryogenesis [ 14 ] . ALDH1A2 in the mouse [ 15 ] and rat [ 16 ] has shown even greater specificity and catalytic efficiency for retinal as a substrate.
DPAB is a potent inhibitor of retinal oxidation with IC 50 values of 0.11 and 0.13 μM for purified mouse and human ALDH1A1, respectively (Table 1).
Spectrofluorometric assays for ALDH activity in HL-60 Cells