Example sentences for: aldh

How can you use “aldh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since there are three molecules with strong absorbances at 340 nm (retinal, retinoic acid, and NADH), we developed a high pressure liquid chromatography (HPLC) assay to assess the ability of DPAB to inhibit retinal oxidation by class 1 ALDH.

  • ALDH1A1 activity was measured on a Shimadzu UV1201 Spectrophotometer at 36.

  • In vitro, purified mouse [ 11 ] , human [ 12 ] , and Xenopus [ 13 ] ALDH1A1 can efficiently oxidize all-trans retinal to all-trans retinoic acid.

  • DPAB is a potent inhibitor of retinal oxidation with IC 50 values of 0.11 and 0.13 μM for purified mouse and human ALDH1A1, respectively (Table 1).

  • The report of the crystal structure of the homotetrameric ALDH1A1 enzyme from sheep liver revealed a substrate tunnel capable of binding retinal which was absent in ALDH2 and ALDH3A1 enzymes [ 9 ] . Likewise, the crystal structure reported for mouse ALDH1A2 revealed a substrate channel which could provide specificity for retinal and exclude short-chain aliphatic aldehydes [ 10 ] .


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