Example sentences for: aldehyde

How can you use “aldehyde” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Aliquots of phosphorylated proteins were added to a reaction containing 120 μg cell lysate, recombinant human E1, 0.25 mg/ml ubiquitin, 1 μM ubiquitin aldehyde, 1 μM okadaic acid, 20 μM MG132, and ATP regenerating system (20 mM ATP, 10 mM creatine phosphate, 0.1 μg/ml creatine kinase).

  • Biosynthetic modifications to the periphery of the tetrapyrrole ring progressively cause withdrawal of electrons from the pyrrole nitrogens, thereby decreasing their basicity [ 20 21 ] . For example, oxidation of the 7-methyl group in Chl a to the electronegative aldehyde of Chl b reduces the pK of the pyrrole nitrogens by 2 pH units.

  • Retinoids are found in a variety of chemical oxidation states, including alcohol, aldehyde, ester, and carboxylic acid functionalities.

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • The peptide aldehyde proteasome inhibitors MG132 and ALLN have previously been used to investigate the post-transcriptional regulation of proteins during physiological processes [ 52, 53].


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