Words similar to aldehyde
Example sentences for: aldehyde
How can you use “aldehyde” in a sentence? Here are some example sentences to help you improve your vocabulary:
Several of the differentially expressed genes, including aldo-keto reductase 1C1 ( AKR1C1 ), aldehyde dehydrogenase 1A1 ( ALDH1A1 ), and alcohol dehydrogenase 1B ( ADH1B ), function in sex steroid and retinoic acid metabolism (Figure 2).
Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.
MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.
The peptide aldehyde proteasome inhibitors MG132 and ALLN have previously been used to investigate the post-transcriptional regulation of proteins during physiological processes [ 52, 53].
Both MAP kinase and STAT pathways are involved in AR-dependent regulation and in ligand-independent activation of the AR [ 18 ] . Differential expression of aldehyde dehydrogenase 1A1 and alcohol dehydrogenase 1B, enzymes that affect retinoic acid biosynthesis, suggest that other signaling pathways may participate in the AR-initiated programs of external genital differentiation [ 19 20 ] .
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