Example sentences for: alagille

How can you use “alagille” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, a rapid search of the Online Mendelian Inheritance in Man database (OMIM [ 18]) for genes associated with the terms 'severe' and 'disorder' confirmed that mutations of GALC, LAMB3, GJB2, JAG1, TGFBI, LPL and LDLR were the origin of serious disorders: Krabbe disease, Herlitz junctional epidermolysis bullosa, autosomal dominant deafness - Vohwinkel syndrome, Alagille syndrome, corneal dystrophy, type I hyperlipoproteinemia and hypercholesterolemia, respectively.

  • Interestingly, jagged-1 is important for epithelial-mesenchymal cell interaction in development [ 50], and mutations in the jagged gene lead to Alagille syndrome, a congenital connective tissue disorder whose hallmarks include craniofacial and vertebral deformities [ 51].

  • Specifically, products of lipid peroxidation are elevated in patients with hepatic hypoxia/reperfusion, obstructive liver disease, alcoholic liver disease, Wilson's disease, Alagille syndrome, sepsis, and inflammatory liver diseases [ 11, 12, 13, 14, 15].

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