Words similar to airway
Example sentences for: airway
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In cell cultures of CD4 T cells and B cells from allergic individuals, addition of anti-CD81 antibody enhances IL-4 production from the T cells [ 19 ] . In mice, either complete lack of CD81, or lack of CD81 on B cells, leads to impaired humoral and Th2 immune responses [ 20 21 ] . Allergen-induced airway hyperresponsiveness is also decreased in CD81 nullmice [ 22 ] . Finally, lack of CD81 on murine T cells diminishes IL-4 production, with reduced expression of ICOS, GATA-3, STAT6 and phosphorylated STAT6 [ 23 ] .
Dezateaux et al . [ 12] compared t PTEF / t E with airway function measured by plethysmography.
The complex changes in lung function, morphology, and gene expression caused by compounds in cigarette smoke involve a combination of direct and indirect effects on cells, but principally center around an increase in airway inflammation as a result of cigarette smoking.
Analysis by immunohistochemistry of airway mucosa of people with atopic asthma after antigen challenge revealed that large numbers of CCR4 + and CCR8 + T cells express IL-4, and CCR4 expression was prominent in people with severe atopic dermatitis, which decreased upon abatement of disease activity [26,43].
Immunofluorescent analysis of airway mucosal biopsies in patients with asthma showed that most T cells co-express IL-4 and CCR4, but, in contrast, T cells in airways of patients with COPD and pulmonary sarcoidosis produce IFN-γ and express high levels of CXCR3, while lacking CCR4 expression [26].