Example sentences for: agrin

How can you use “agrin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Again in agreement with AChR observations, α-DG aggregate density is increased by LN1 but not agrin (Figure 4D) - however in this case it appears that this increase is prevented by agrin, while in the case of AChRs the combination follows the LN1 alone phenotype of increased aggregate density.

  • Average receptor expression was found to be significantly increased following exposure to agrin, and less so although still significantly in response to LN1 (Figure 2A).

  • Laminins are major components of the extracellular matrix and exist in many isoforms with varying functions including cell adhesion, neurite outgrowth, and cellular signaling [ 7 8 9 10 ] . Laminin binds agrin [ 11 ] , and colocalizes with AChR aggregates [ 12 13 14 ] . It also binds with α-Dystroglycan (α-DG), an important part of the dystrophin/utrophin glycoprotein complex (Reviewed in [ 15 16 ] ). The dystrophin complex is also found concentrated at the neuromuscular junction with AChRs and laminin, and for this and other reasons is thought to be involved in both formation and maintenance of the NMJ [ 2 17 18 19 20 21 22 23 ] .

  • α-DG aggregate size follows a similar pattern of increase by LN1 (alone or in combination) but not agrin (Figure 4C), but in this case it is the same as the finding with AChRs (Figure 2C).

  • We did not find the substantially larger number of LN1 (as opposed to agrin) induced aggregates reported previously [ 1 ] , perhaps because of the shortened application of laminin used in the presented experiments.


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