Words similar to acylcarnitine

Example sentences for: acylcarnitine

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It has been noticed that if a patient is suspected of having a mitochondrial disease, abnormal carnitine esters may help with the diagnosis, [ 38 ] and abnormal acylcarnitine profiles do not exclusively indicate fatty acid oxidation disorders [ 39 ] . Although the abnormal carnitine ester present in the proband is elevated in organic acidemias and is not usually present in mitochondrial cytopathies, we speculate that due to compromised ATP synthesis, secondary alterations may be generated in these patients by changes in mitochondrial protein synthesis, decrease in Krebs cycle intermediates and increased free radical formation, that could be responsible for a secondary impairment of mitochondrial biotin dependent carboxylases, but further elucidation is necessary before we could arrive to a conclusion in this regard.
Orotic aciduria and abnormal acylcarnitine profile as potential markers of mitochondrial disease