Example sentences for: actomyosin

How can you use “actomyosin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The procedure for the histochemical demonstration of actomyosin ATPase was employed as described by Goth and Samara [ 24 ] . Briefly, fixed sections were washed in rinse solution [18 mM calcium chloride in 100 mM tris (hydroxymethyl) aminomethane (Tris), pH 7.8] for 1 minute, preincubated either in 50 mM potassium acetate in 18 mM calcium chloride at pH 4.35 (for acid-stable myosin ATPase, type I slow twitch muscle fibers), or in 18 mM calcium chloride in 100 mM 2-amino-2-methyl-1-propanol at pH 10.

  • Previous studies suggested that both steps are facilitated by the action of actomyosin, which requires ATP hydrolysis [ 45].

  • Caldesmon is likely to play a modulatory role on the production of smooth muscle force via a tethering of actin to myosin [ 11 ] and/or of its effects on the actomyosin ATPase [ 12 13 14 ] . Similarly, TM does not seem to function as a major regulatory protein, but modulatory effects due to its ability to maintain the actin filamentous structure [ 15 ] , to inhibit the Ca 2+-ATPase activity [ 16 ] , alter the cytoskeletal dynamics [ 17 ] and improve actin filament flexibility during the contraction/relaxation cycle [ 18 19 ] have been well documented.

  • In panel C, type I (dark stain), IIa (light stain), and IIb-IId/x (intermediate stain) fibers can be identified based on the myofibrillar actomyosin ATPase histochemical staining procedure [ 18 ] . Immunohistochemistry was used to positively identify subpopulations of fibers expressing only the 2B MHC.

  • For example, growth factor-induced localization of actin mRNA to the leading edge of fibroblasts is a dynamic, regulated process requiring actomyosin interactions and activation of the RhoGTPase pathway, as well as specific signal sequences in the 3' UTR of the message [ 9 10 11 12 ] . Moreover, disruption of the actin cytoskeleton using pharmacological agents also blocks the association of β-actin mRNA with microfilaments and prevents localization of the transcript to the cell periphery [ 7 13 ] . Mechanical forces exerted on cell surface integrin receptors, which anchor the actin cytoskeleton to the extracellular matrix, also produce changes in the localization of poly(A) mRNA and ribosomal proteins inside the cell [ 14 ] . Importantly, the localization of transcripts can serve as a key regulatory step in gene expression as inhibition of mRNA targeting can significantly impact cell function.


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